James Dowling, M.D., Ph.D.

Associate Professor

Hospital for Sick Children
Peter Gilgan Centre for Research & Learning, 15-9703
686 Bay St.
Toronto ON M5G 0A4

Phone #: 416-813-8980 (x308980)

Admin: irina.iovu@sickkids.ca




diseases of skeletal muscle, phosphoinositide signalling, zebrafish


Postdoctoral Fellow:  University of Michigan
M.D., Ph.D.:  University of Chicago;   Residency: Children's Hospital of Philadelphia
B.Sc., M.Sc.:  Yale University

Fields of Interest:

  • Genetic Models of Development and Disease
  • Molecular Medicine and Human Genetics


Research Interests:

My laboratory seeks to understand the pathogenic mechanisms of and develop therapies for childhood muscle diseases.  We combine gene discovery and model systems research to define disease pathology and identify treatments.  Our favorite model system is the zebrafish, and we are interested in the role of endolysosomes in muscle biology.


Accepting Rotation Students: