Andrew Bognar, Ph.D.
University of Toronto
Medical Sciences Building, Room 4259
1 King's College Circle
Toronto, ON, M5S1A8
Phone #: 416-978-5854
Structure and functional of folylpolyglutamate synthetase
Postdoctoral Fellow: Washington State University; Concordia University; John Hopkins University
Ph.D.: McGill University
B.Sc. (Hon): McGill University
Fields of Interest:
- Cellular and Molecular Structure and Function
- Molecular Microbiology and Infectious Disease
Structure and Function of folylpolyglutamate synthetase the enzyme that allows folate coenzymes and antifolate drugs to remain inside cells by forming polyglutamates. Studying the reaction mechanism by in vitro mutagenesis, kinetics and HPLC for product identification. Regulation of one-carbon metabolism in yeast by glycine. Role of antifolates in inflammatory diseases.
Not Accepting Graduate Students