Hue Sun Chan, Ph.D.
University of Toronto
Medical Sciences Building, Rm. 5363
1 King's College Circle
Toronto, ON, M5S 1A8
Phone #: 416-978-2697
Theoretical and Computational Investigations of Protein Folding, Interactions, and Evolution
Postdoctoral Fellow: University of California at San Francisco
Ph.D., University of California at Berkeley
Fields of Interest:
- Cellular and Molecular Structure and Function
- Computational and Systems Biology
Protein folding and interactions are physico-chemical processes. Our group's overall research goal is to elucidate their underlying energetics. To this end, a main emphasis of our effort is to develop proteinlike heteropolymer models with coarse-grained interactions and simplified representations of chain geometries. The rationale of these approaches is to capture the essential physics and at the same time allow for a broad coverage of the protein conformational space - and also a broad coverage of the sequence space for evolutionary studies - that is not readily achievable currently in higher-resolution models.