Julien Muffat, Ph.D.

Assistant Professor

Hospital for Sick Children
Peter Gilgan Centre for Research & Learning, Rm. 17-9708
686 Bay St.
Toronto, ON M5G 0A4

Phone #: 416-813-7654 ext. 309997

Admin: julie.meltzer@sickkids.ca

Web Site: http://www.sickkids.ca/AboutSickKids/Directory/People/M/julien-muffat.html


Postdoctoral Fellow: Whitehead Institute for Biomedical Research, MIT
Ph.D.: California Institute of Technology
M.Sc., B.Sc: Université de Paris

Fields of Interest:

  • Genetic Models of Development & Disease

  • Cellular & Molecular Structure & Function


Research Interests:

I develop novel 3D cultures derived from human iPSCs to study degenerative diseases of the brain. I focus on neuro-immune aetiologies of diseases ranging from autism to Alzheimer's, highlighting the role of microglia in establishing neuronal dysfunction. CRISPR/Cas9 genome engineering allows functional interrogation of disease-associated variants expressed exclusively in microglia.


Accepting Rotation Students: