Andrew Spence, Ph.D.


MaRS Centre, West Tower
661 University Ave., Rm. 1534
Toronto, ON, M5G 1M1

Phone #: 416-978-6406

Web Site


Determination of sex-specific cell fates in Caenorhabditis elegans via a novel form of epigenetic regulation


Postdoctoral Fellow:  MRC Laboratory of Molecular Biology, U.K.
Ph.D.:  University of British Columbia
B.Sc.:  University of Winnipeg

Fields of Interest:

  • Cellular and Molecular Structure and Function
  • Genetic Models of Development and Disease

Research Interests:

We study genes that determine sex-specific cell fates in Caenorhabditis elegans. We have described a novel form of epigenetic regulation that depends upon maternally contributed RNA to license gene expression in the germ line of the next generation, and we are using genetic and genomic approaches to understand its mechanism.


Not Accepting Graduate Students