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Brenda Andrews

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Brenda Andrews, Ph.D.

Professor

Address:
University of Toronto
The Donnelly Centre, Rm. 1308
160 College St.
Toronto, ON, M5S 3E1

Phone #: 416-978-8562

Web Site: http://sites.utoronto.ca/andrewslab/homepage.html


Research:

Studying simple yeast cells to understand human cells


Education:

Postdoctoral Fellow: University of California, San Francisco
Ph.D.: University of Toronto
B.Sc.: University of Toronto


Fields of Interest:

  • Genetic Models of Development and Disease

  • Functional Genomics and Proteomics

 

Research Interests:

The Andrews lab uses functional genomics coupled with yeast genetics and cell biology to study cell cycle transcription factor pathways and mechanisms of cell cycle regulation. Current projects include: 1) systematic synthetic dosage lethality (SDL) screens using automated yeast genetics to define targets of protein kinases; 2) a 'phenomics' project that uses high through put fluorescence microscopy to define biological networks and to map cell cycle transcription factor pathways; 3) collaborations with the Boone, Hughes and other labs to map genetic networks controlling cell cycle progression and cell polarity in yeast.

 

Accepting Rotation Students:

Yes

 

 

 

 

Irene Andrulis

Irene Andrulis, Ph.D.

Professor

Address:
Mt. Sinai Hospital
LTRI, Room 984
600 University Ave.
Toronto, ON, M5G 1X5

Phone #: 416-586-8256

Web Site: http://www.lunenfeld.ca/researchers/Andrulis


Research:

Genetic alterations in breast cancer and sarcoma


Education:

Postdoctoral Fellow:  University of Toronto
Ph.D.:  University of California, Irvine
B.Sc.:  University of Pennsylvania


Fields of Interest:

  • Cellular and Molecular Structure and Function
  • Molecular Medicine and Human Genetics

 

Research Interests:

My laboratory conducts multi-disciplinary studies to identify genetic alterations that play a role in breast cancer and sarcoma and to determine their clinical importance.  Our goals are to explore the biology of these genetic alterations, to aid in diagnosis and treatment, and to discover novel targets for therapeutics.

 

Accepting Rotation Students:

No

 

Gary Bader

Gary Bader, Ph.D.

Professor

Address:
University of Toronto
The Donnelly Centre, Rm. 602
160 College St.
Toronto, ON, M5S 3E1

Phone #: 416-978-3935

Web Site: http://baderlab.org/


Research:

Organization and evolution of biological systems


Education:

Postdoctoral Fellow:  Memorial Sloan-Kettering Cancer Center
Ph.D.: University of Toronto  
B.Sc.: McGill University


Fields of Interest:

  • Computational and Systems Biology
  • Functional Genomics and Proteomics

 

Research Interests:

We study the organization and evolution of biological systems using computational biology and bioinformatics techniques. This work is supported through the development of open-source biological pathway and network databases and visualization and analysis software.

 

Accepting Rotation Students:

No

 

Alan Bernstein

Alan Bernstein

Adjunct Professor

Address:
Canadian Institute for Advanced Research, Suite 505
MaRS West Tower, 661 University Ave.
Toronto, ON M5G 1M1

Phone #: 416-971-4255

Web Site: http://www.cifar.ca/cifar-staff


Research:

Intersection of research and public policy, especially science policy


Education

Postdoctoral Fellow:  Imperial Cancer Research Laboratories, U.K.
M.Sc, Ph.D.:  University of Toronto
B.Sc.:  University of Waterloo


Fields of Interest:

  • Genetic Models of Development and Disease

  • Molecular Medicine and Human Genetics

 

Research Interests:

My current research interests centre around the intersection of research and public policy, especially with regard to science policy.

 

 

Benjamin Blencowe

Benjamin Blencowe, Ph.D.

Professor

Address:
University of Toronto
The Donnelly Centre, Rm. 1016
160 College St.
Toronto, ON, M5S 3E1

Phone #: 416-978-3016

Web Site: http://sites.utoronto.ca/intron/


Research:

Regulation of gene expression and alternative splicing


Education:

Postdoctoral Fellow:  Massachusetts Institute of Technology
Ph.D.:  EMBL, Heidelberg, Germany and University of London, UK
B.Sc (Hon):  Imperial College London, UK


Fields of Interest:

  • Cellular and Molecular Structure and Function
  • Functional Genomics and Proteomics

 

Research Interests:

Our research focuses on mechanisms underlying the regulation of gene expression and how these mechanisms go awry in human diseases. Most of our research is directed at understanding how alternative splicing is integrated with other layers of gene regulation to control fundamental biological processes, such as cell fate determination.

 

Accepting Rotation Students:

Yes