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Brenda
J. Andrews - Cell Cycle
Control
Irene
L. Andrulis - Gene amplification,
cancer
Jane
Aubin - Cell and Molecular
Biology of Mesenchymal Stem and Osteoprogenitor
Cell Differentiation
Gary
Bader - Computational network
biology
Benjamin
J. Blencowe
- Regulation of pre-mRNA processing in mammalian
cells
Andrew
Bognar - Structure and Function
of FPGS
Charlie
Boone - Mechanisms regulating
actin assembly and polarized cell morphogenesis
Gabrielle
Boulianne - Genetic Models
of Neuronal Development, Function and Disease
Julie
Brill - Role of phosphatidylinositol
lipids and lipid kinases in Drosophila development
John
Brumell - Salmonella
- mechanisms and pathogeneis of disease
Martha
Brown - Adenovirus replication
Amy Caudy
Hue
Sun Chan - Theoretical and
Computational Approaches to Protein Folding
Brian
Ciruna-
Molecular
genetic regulation of embryogenesis, using the zebrafish
Danio rerio
Julie Claycomb - Our goal is to understand how small RNAs influence chromatin and impact development.
Alan.
W. Cochrane - HIV-1 gene
expression
Richard
A. Collins - RNA structure
and evolution
Sabine
Cordes - Molecular Genetics
of Hindbrain Patterning and Serotonergic Neuro Development
Leah
E. Cowen - Microbial genomics,
evolution, and infectious disease.
Joseph
G. Culotti
- Neuronal development
Alan
R. Davidson
- In Vitro and In Vivo Studies of and Protein-Protein Interactions and Macromolecular Assembly.
W.
Brent Derry - The
application of genetics, functional genomics and
biochemical techniques to understand the p53 signaling
network.
James
W. Dennis - Glycosyltransferases
in Cancer and Inflammmation
John
E. Dick - Generation of
in vivo models in immunodeficient mice to
characterize normal and leukaemic human haematopolesis;
role of oncogenes in human leukaemic transformation
and progression
Peter Dirks
Daniel
Durocher - DNA damage signaling
and checkpoint control
Aled
Edwards - Mechanism by
shich yeast olymerase II transcription is regulated
at the level of elongation
Sean
E. Egan - Studies on Endocytosis
of cell surface receptors, Notch activation and
Mouse Mammary Gland Development
James
Ellis - Induced pluripotent stem cells and the epigenetics of gene therapy vectors
Andrew
Emili - Proteomic and bioinformatic
analyses of model organisms Alex Ensminger- (Experimental) evolution, genomics, and medical microbiology.
Oliver Ernst - Structural Neurobiology
Lori
D. Frappier - Mechanisms by which viruses persist and induce cancer in human cells, and the roles of human MCM proteins in DNA synthesis
Andrew Fraser - Predicting the effect of any single inherited genetic mutation
Barbara
E. Funnell - Chromosome
and plasmid partition
Brenda
L. Gallie - Retinoblastoma
oncogenesis
Guri
Giaever - Chemical Genomics
Anne-Claude
Gingras Dr. Gingras aims
to better understand how phosphatases are regulated,
and to decipher the impact of each phosphatase on
cell growth and proliferation.
Scott
Gray-Owen -Cellular responses
to the pathogenic Neisseria
Jack
F. Greenblatt -Transcriptional
regulation
Tom Hudson - Cancer Genetics
Timothy
Hughes - Functional genomics,
RNA processing, regulation of gene expression, DNA
microarrays
Chi-chung
Hui - Molecular genetics
of mammalian development
C.
James Ingles - Eukaryotic
transcription
Sadhna
Joshi - ANTI-HIV-1 Gene
Therapy
David
Kaplan - Signal transduction
pathways regulating the survival and growth of neurons
Lewis
E. Kay - NMR of proteins
Phillip Kim Computational Biology, Protein Networks, Genetic Variation, Signaling Pathways
Henry
Krause - Whole-animal proteomics, ribonomics, drug discovery
Brigitte
Lavoie - Our overall goal
is to understand (1) how mitotic chromosome condensation
impacts the transmission of genetic material and
(2) the molecular mechanism of higher-order chromosome
folding
Howard
D. Lipshitz - Molecular
genetics of Drosophila development
Jun
Liu - Post-Genome TB research:
an integrated approach
Helen
McNeill - We are interested
in how cells become organized into tissues in development
Marc
Meneghini-
Epigenetic regulation in yeast and during animal
development
M.
Stephen Meyn - Human molecular
genetics, cancer and aging, genomic stability
Freda
Miller - Neuronal stem
cells, neuronal growth, survival and apoptosis
Jason
Moffat Our lab uses
lentiviral RNAi and imaging technologies to understand
how different growth signaling pathways contribute
to cancer metabolism.
Michael
Moran -
Mechanisms
of signal transduction related to cancer; the development
and application of functional proteomics approaches
related to drug and biomarker discovery; signal
transduction.
Quaid
Morris - Development and
application of adaptive algorithm for analysing
large-scale biological datasets.
Andras
Nagy - Application of mouse
genetics to study development and to connect to
human disease
William
W. Navarre -Bacterial
evolution and virulence.
Corey
Nislow - Chemical biology
Kenichi Okamoto
Lucy
Osborne - The molecular
basis of Williams-Beuren syndrome (WBS) and Functional
Annotation of the Mouse Genome
Emil
F. Pai - Structure and
function of proteins
John
Parkinson - Understanding
the molecular mechanisms controlling cell processes
and their medical and biological implications
Anthony
J. Pawson - Intracellular
signalling
Bret Pearson - Stem cell biology and regeneration in freshwater planarians
Christopher
E. Pearson - Mechanisms
of Genome Stability and Trinucleotide Repeat diseases
Laurence
Pelletier - We are interested in understanding the cellular mechanisms that regulate cell cycle progression and chromosome segregation in human cells, with a particular emphasis on centrosome/cilia biogenesis. Towards this goal we use functional genomics in combination with high resolution spatiotemporal imaging methods to study these processes and comprehend how they go awry in cancer.
Peter
Ray - Duchenne muscular
dystrophy
James
M. Rini - X-ray crystallography
of proteins
John
Roder
- Cell adhesion molecules in the brain
Johanna
M. Rommens - Human Genetics
Mechanisms of Genetic Disease Gene Maps
Janet
Rossant - Early mouse embryogenesis
Fritz Roth- Designing and interpreting large-scale experiments to understand pathway structure and its relationship to phonotype and human disease.
Peter
J. Roy - Guided Cell Migration and Chemical Biology
William Ryu - The movement and behavior of E. coli and C. Elegans
Stephen
Scherer - Genome mapping
and sequencing: application to human disease studies
Ian
Scott - Heart development;
developmental biology; zebrafish genetics; heart
morphogenesis; zebrafish genomics/transgenic tool
development
Sachdev Sidhu - Cell proteins – the software of the cell.
Jacqueline
Segall - Regulation of
gene expression
Frank
Sicheri - Structural basis
of protein kinase regulation in cell signaling
Katherine
Siminovitch - Genetic basis
of autoimmune responses and X-linked immune deficiency
disease
Craig Smibert - Translational regulation during development
Andrew
Spence -
Sex determination in Caenorhabditis elegans
Igor
Stagljar - The laboratory
uses a combination of molecular, cellular, genetic,
genome, and proteome approaches to study the function
of many yeast and human membrane proteins as well
as proteins involved in the maintenance of genome
stability in humans.
Lincoln Stein - Informatics & Bio-computing
Boris
Steipe - Molecular Systems
Engineering and Bioinformatics
Chetankumar
Tailor - Retroviruses,
retrovirus receptors, gene therapy
Derek
van der Kooy - Neural development,
Neurobiology of motivation, Learning and memory
genes
Andrew
Wilde - Cell Division and Oogenesis
Shoshana
Wodak - Computational Structural
Biology and Bioinformatics: Linking the molecular
and cellular levels.
Jeff
Wrana - TGF-b signalling
Mei
Zhen - Nervous system:
development, function and disease
Zhaolei
Zhang - Bioinformatics
and Computational Genomics |
Welcome
to our faculty listing page. We invite you to explore
our diverse faculty and read about their many interests
and the opportunities offered throughout our department.
We encourage you to contact individual labs to learn
more about our ongoing research.