Speaker: Dr. Rameen Beroukhim
Affiliation: Harvard Medical School
Host: Dr. Fritz Roth
Date & Time: December 7th - 4PM
Place: FitzGerald Building, Room 103

I will discuss three stories about the cancer genome in relation to tumorigenesis, progression, and therapeutics.  The first concerns a novel rearrangement in pediatric gliomas, and the complex mechanisms by which it promotes tumorigenesis.  The second concerns the genetic changes endometrial cancers undergo as they progress from pre-invasive lesions to metastatic cancer.  The third concerns vulnerabilities unveiled by cancer genome alterations that do not rely on targeting oncogenic pathways.

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