Discovery a mechanism through which a tiny RNA, miR-126, regulates self-renewal in normal and cancer blood stem cells (Cancer Cell 2016, 29: 214-28) A team lead by Dr. John Dick revealed that this micro RNA has opposing effects in normal blood stem cells and those associated with the blood cancer acute myeloid leukemia. In cancer stem cells, miR-126 targets core cellular signalling pathways to prevent differentiation and promote resistance to chemotherapy.

Dr. John Dick

Dr. John Dick