Dr. Daniel Durocher

Dr. Daniel Durocher

Discovery of how cells control DNA repair that is key to editing human genes as a means to cure disease (Nature 2015, 528: 422-6). Imagine if we could correct genetic errors inside diseased organs and return them to health? Gene editing, a process by which inherited mutations can be fixed, has become possible, but it only works in cells that are dividing, which are scarce in our bodies. A team led by Dr. Daniel Durocher has discovered a way to perform this kind of precise gene editing in non-dividing, fully differentiated cell types. The key lies in control of homologous recombination, which is the method by which our cells mend mistakes in DNA caused by copying of the genetic material during cell division. Click here to learn more.