The premise the course is that cancer is largely a product of the sequence-to-phenotype continuum: DNA-to-RNA-to-Proteome-to-Phenotype (i.e. cancer). The course comprises a series of lectures delivered by leading proteomics experts and researchers. Students will learn about mass spectrometry-based proteomics including spectral analysis, and tissue proteome profiling as methods to discover cancer drivers and biomarkers, and to define and compare phenotypes such as normal versus cancer; drug responsive versus drug resistant. Innovative high-content proteomics technologies will be introduced that have been developed and applied to systematically interrogate proteomes for protein interactions associated with disease, cell regulation, and drug responsiveness.

Course Outline

Coordinators: Dr. Michael Moran
Instructors: Michael Moran, Hannes Rost, Brian Raught, Thomas Kislinger, Igor Stagljar
Dates:  Thursdays, Sept. 19 to Oct. 24 2019
Time:  1:00 pm to 3:00 pm
Place: Peter Gilgan Centre for Research and Learning (PGCRL) 17.9701
Enrollment: Class size is limited to 10-15 students

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