Topics will include fate mapping and lineage analysis, forward genetic approaches, the production and use of genetic mosaics, reverse genetics, conditional mutagenesis strategies, and in vivo imaging technologies. Discussions will focus on the merits and limitations of experimental techniques across various animal model systems. A basic understanding of embryonic development is assumed.
The format of this course will be journal club style presentations by students of selected research papers, followed by a general discussion. Student grades will be based on presentations (50%), participation in discussion (50%).