The course provides a survey of current and emerging approaches in functional genomics and proteomics, with a focus on experimental design and data interpretation. The course consists in a series of presentations and guided discussions by researchers that are developing cutting-edge functional genomics and/or proteomics approaches. Topics to be covered this year will include: a) Next Generation nucleic acid sequencing, b) Genetic interactions in model organisms, c) Proteomics and protein interactions, d) High content screening, e) CRISPR technologies, and f) Systematic assay development.
Student grades will be based on participation to the discussions, presentation of a research paper in a journal club format, submission of a NSERC-style grant application, and a short presentation of the application to the class.
Coordinator: Dr. Anne-Claude Gingras & Dr. Andy Fraser
Dates: Tuesdays, October 9 - November 27, 2018, 4 - 6p.m.
Place: Mount Sinai Hospital, 600 University Ave, Rm 1062
Enrollment: Class size is limited to 12 students
Note: Separate credit cannot be given for this topic if students have already taken Biochemistry JTB2010H