Over the last few years molecular genetic analyses have uncovered a variety of molecular mechanisms that can lead to human psychiatric and neurobiologic disorders. Mutations that affect everything from regulated secretion of neurotrophins, biosynthetic enzyme activity, and alternative splicing to epigenetic transcriptional regulation have been shown to affect mental health. For most any molecular mechanism, nervous system function provides one of the most sensitive biologic read-outs. In this six week course, students will present and discuss the latest findings on molecular mechanisms involved in neurobiologic and psychiatric disorders, which include autism, schizophrenia, and bipolar and phobic disorders. Aside from the presentation and active participation in discussions, students are expected to write a mini review.
Coordinators: Dr. Sabine Cordes
Dates: November - December, 2019