This course will cover topics related to the mechanisms underlying post-transcriptional control of gene expression in eukaryotes. Students will be organized into 6 groups. Each group will be assigned a topic, develop a 60 min power point-assisted lecture that would be suitable to teach this topic to a class of first year graduate students, and present the lecture to the class. The 6 topics will be:
- RNA/protein interactions
- mRNA splicing,
- mRNA export
- mRNA localization
- translational regulation, and
- control of mRNA stability
Each group should consult with Drs. Smibert and Lipshitz regarding the content of each topic lecture.
Each class will begin with a student-led lecture, which will be followed by a discussion of a paper related to the lecture. Note that the lecture should be developed with the content of the discussion paper in mind.. Note that the lecture should be developed with the content of the discussion paper in mind.
Coordinator: Dr. Howard Lipshitz and Dr. Craig Smibert
Date: Thursdays, November 1 - December 6, 2018, 10:00 a.m. - 12:00 p.m.
Organizational meeting: Thursday October 4, 2018, 12:00 p.m. - 1:00 p.m.
Place: Room 1522, MaRS West Tower
Enrollment: 8-24 students