Principles of Genetic Analysis I: Bacterial Genetics

Genetics is an experimental science. MGY314H is a laboratory course in bacterial genetics; students perform and analyze genetic experiments over the 12-week period. Students will perform a variety of genetic crosses and mutant hunts, and learn phenotypic characterization in bacteria. Most of the class time is in the lab, with some tutorials and short lectures to supplement the understanding of genetics.

The emphasis in MGY314H is to learn the concepts of genetics; how to apply them and how to interpret them. The model we use in this course is Escherichia coli, which is the best studied gram-negative bacterial species. It is often the model of choice in the study of more harmful bacterial species because many principles of its biology apply to all bacteria (and in fact, to all organisms). Finally, it is also the organism that the scientific world uses for molecular biology, and many of the original genetics defined in E. coli has led to important tools for diagnosis and scientific research.

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Prerequisite: BIO230H1/BIO255H1, BIO260H1/HMB265H1

Course Coordinator: Dr. Barbara Funnell

Offered: September to December 2019 - Thursdays (1:00 p.m. to 5:00 p.m.)

Location: DTL (MSB) 3280, 3282, 3379

Textbook: Molecular Genetics of Bacteria, 4th edition, Snyder, L., Peters, J.E., Henkin, T.M., and Champness, W. American Society for Microbiology (ASM) Press, 2013.